Throughout the course, you will engage in hands-on manipulation of a sample dataset, offering a comprehensive experience in contemporary bioinformatics. The content emphasizes gaining proficiency in using R, Python, and UNIX/Linux commands within the context of bioinformatics. This course serves as a natural progression from the Fundamentals of Bioinformatics (NA00AK46), complements the theoretical knowledge acquired in Introduction to Population Genetics and Molecular Ecology (NA00AK27), and applies the command-line skills acquired in Data Wrangling (NA00AR18). While lectures provide a foundational understanding of the main steps and principles behind data analyses, the primary focus is on practical experience in handling and analyzing large datasets.